( ilj ) 
clifpute, thele two be allow’d to have died of Inocula- 
tion, we muft eftimate the hazard of dying of the In- 
oculated Small Pox, as far as can be collected from 
our own Experience, to be that of x out of 182, or 
one out of 91. 
The Reverend Mr. Mather^ in a Letter dated March 
10. 1721. from Bofton in New England^ gives an Ac- 
count, That of near 300 inoculated there^ ^ or 6 died 
upon tt or after it^ but from other E>ifeafes and Ac- 
cidents^ chiefly from having taken the Infection in the 
common way by Injpir at ion^ before it could be given' 
them in this way ofTranfplantation. 
If, as we have done before, to avoid all occafion of 
difpute, we allow 5' out of thefe 300 to have died of 
the Small Pox by Inoculation, notwithftanding what 
Mr. Mather has faid of their dying by other Acci- 
dents or Difeafes ; the hazard of Inoculation will 
thence be determin’d to be that of i in about 60. But 
here it muft be oblerv’d, that by all the Accounts 
from New England, the Operators there appear not 
to have been fo cautious in the choice of their Subjeds, 
as here in England. For Mr. Mather tells us, that 
the Perfbns inoculated were young and old, from i 
Tear to 70, weak and flrong ; and by other relations 
we are inform’d, that kF omen with Child, and others 
even in Childbed, underwent the Operation. Appa- 
rently the Greatnefs of the Danger they were in, from 
the Infedion in the natural Way, which then raged 
among them with the utmoft Fury, made them the 
more adventurous. 
VTe come now. Sir, to the fccond Part of our De- 
fign, which is to form an Eftimate’ of the Hazard, 
which all Mankind, one with another, are under of 
dying of the namral Small Pox, that, by comparing 
this with the Hazard of Inoculation, the Publick may 
Mm2 be 
