Chapter 1 1 
DR. ZACNY: You were talking about the first study when we looked at 50 
and 100 percent of hole blocking. 
DR. TOWNSEND: 1 understand. 1 would like to talk with you some more 
about this, because we have some data at R.J. Reynolds where we have gone 
directly to an inhydrin staining test where the saliva on the filter, in fact, 
stains with inhydrin; therefore, we can visually see how much saliva has 
gotten up to the vents. 
What we have seen in a study with a number of subjects is that the spent 
butts show some blockage, but it is a very infrequent phenomenon. So, I 
would like to talk to you further about that. Perhaps we can propose doing 
some additional studies. 
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