Section IV 
for the poor correlation between HCN yield and levels of plasma thiocyanate 
and saliva thiocyanate. 
Rickert and colleagues (1980) indicated that aldehydes, gas-phase 
constituents of tobacco smoke, are known to be ciliatoxic and may not be 
removed to a substantial degree from cigarette smoke by filters. Acrolein, a 
toxin restricted in occupational and industrial settings, also may contribute 
to the chemical toxicity of tobacco smoke. In a study of 102 brands of 
Canadian cigarettes, Rickert and colleagues found that tar level was a poor 
predictor of total aldehydes and acrolein delivery. The effect of changes in 
smoking patterns on phenol, glycerol, catechol, hydroquinone, palmitic acid, 
and neophytadiene are shown in Tables 2 through 5 (Schlotzhauer and 
Chortyk, 1983). 
PROPOSALS TO At least three proposals have been published for changes in the 
CHANGE THE FTC FTC cigarette test method. Kozlowski and colleagues (1982b) 
TEST METHOD made a proposal addressing the issue of the variability in human 
smoking behavior. These investigators suggested a three-level (i.e., light, 
average, and heavy) machine regimen linked to a color-matching technique 
to help smokers gauge the extent of puffing on a given cigarette — the darker 
the stain, the greater the exposure, with the tar stains keyed to a range 
of tar doses. Rickert and colleagues (1986) proposed an estimate based 
on average yields of tar, nicotine, and carbon monoxide per liter of smoke. 
Henningfield and coworkers (1994) proposed that multiple tests be used: 
an average smoking test and a heavy smoking test. The heavy smoking test 
would include vent-blocking conditions for those cigarettes incorporating 
ventilation holes and if it is possible for those holes to be blocked by the 
smoker's lips or fingers. 
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