MINUTES OF MEETING - March 6-7 
3 
I. CALL TO ORDER AND OPENING REMARKS 
Dr. Jane Set lew, chairperson, called the meeting to order at 9:00 a.m., 
March 6, 1980. Dr. Setlow introduced Dr. Kenneth Bems, a new Recombinant 
DNA Advisory Committee (RAC) member. 
Dr. Setlow then called the attention of the RAC to two items, tab 847 
and tab 848 which had been included in the material sent to the RAC. She 
noted that tab 847 is a report of the frequency in nature of Escherichia 
coli strains that can serve as recipients and/or hosts for genetic infor- 
mation carried by various Escherichia coli recombinant DNA host-vector 
systems. She said that tab 848 deals with the production of a choriogona- 
dotrcpin-1 ike factor by a microorganism tentatively named Progenitor 
cryp toe ides . 
II. MINUTES OF DECEMBER 6-7, 1979 MEETING 
The RAC reviewed the minutes of the previous meeting (tab 863). Dr. Walters 
said he believed there were two substantive errors in the minutes: on page 
27, line 32, a semicolon should follow the word "experimental;" on page 
31, line 15 should read "host-vector systems are excepted from. ..." 
Dr. Bems noted that on page 15, line 7, he was credited with making a 
motion concerning an RAC major action. He said he believed Dr. Baltimore 
actually made this motion. 
Dr. Goldstein requested a cross indexing in the discussion of the Foot and 
Mouth Disease (FMD) proposal beginning on page 4, of the paragraph on 
page 23 which states that Dr. Krimsky submitted to the RAC material pertinent 
to the FMD discussion. In addition, he requested that an index of the 
material supplied by Dr. Krimsky be appended to the minutes. 
Mr. Thornton moved approval of the minutes. The minutes, with the changes 
incorporated, were unaminously approved, with the exception of Dr. Parkinson 
who abstained. 
III. REPORT OF MEETING OF FEDERAL INTERAGENCY ADVISORY COMMITTEE ON RECOMBINANT 
ENA RESEARCH 
Dr. Joseph Perpich, Executive Secretary of the Federal Interagency Advisory 
Committee (FIC) reported on the FIC meeting (tab 817, 856) of February 27, 
1980. He noted that Dr. Maxine Singer, NCI, NIH, had presented a summary 
of scientific advances in the area of recombinant ENA technology, 
Dr. William Gartland, ORDA, NIH, had reviewed the recent revisions in 
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