DEPARTMENT OF HEALTH AND HUMAN SERVICES 
PUBLIC HEALTH SERVICE 
NATIONAL INSTITUTES OF HEALTH 
BETHESDA. MARYLAND 20205 
December 3, 1980 
TO: 
Recipients of Guidelines for Research Involving 
Recombinant DNA Molecules 
FROM: Office of Recombinant DNA Activities, NIH 
SUBJECT: Effective Date of the Revised Guidelines 
The Federal Register inserted an effective date of November 21, 1981 by 
mistake on page 77372 of the Federal Register of November 21, 1980. 
The correct effective date of the revised Guidelines is: 
NOVEMBER '21, 1980 
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