12496 
Federal Register / Vol. 45, No. 39 / Tuesday, February 20, 1980 / Notices 
National Institutes of Health 
National Institute of Allergy and 
Infectious Diseases; Meeting 
Notice is hereby given of a Workshop 
to consider two areas within the NIH 
Program to Assess the Risks of 
Recombinant DNA Research. This 
Workshop is being sponsored by the 
National Institute of Allergy and 
Infectious Diseases as part of its 
responsibility to implement the Program. 
The meeting will be convened at the 
Huntington Sheraton Hotel. Pasadena, 
California on April 11 and 12, 1980. 
This Workshop is designed to define 
the scientific issues and assess the 
potential risks of (1) possible direct 
adverse effects of hormone-producing 
strains of E. coli K-12, and (2) the 
possible occurrence of autoantibodies or 
autoreactive cells due to the production 
of eukaryotic polypeptides (including 
hormones] by E coli K-12 should they 
colonize higher organisms. These 
potential risks are being considered 
because there is still debate over the 
degree of possible risk, even though E. 
coli K-12 has apparently lost those 
known characteristics that are required 
for colonization of the normal intestinal 
tract. The meeting will bring together 
outstanding scientists from the fields of 
immunology, endocrinology, physiology, 
microbiology, infectious diseases and 
other appropriate disciplines. The entire 
meeting is open to the public but such 
attendence is limited to the space 
available. 
Further detailed information can be 
obtained from Dr. John E. Nutter, Chief, 
Office of Specialized Research and 
Facilities, National Institute of Allergy 
and Infectious Diseases, National 
Institutes of Health, Bethesda, Maryland 
20205, (301) 496-5643. 
Dated: February 15, 1980. 
Suzanne L. Fremeau, 
Committee Management Officer, National 
Institutes of Health. 
(FR Doe. 80-5W7 Filod t-tS - « MS am] 
BILLING COOE 4110-M-M 
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