TABLE OF CONTENTS 
Part 
Page 
1.. . 
11.. 
III. 
IV. . 
V. .. 
VI. . 
VII. 
VIII 
IX. . 
X. .. 
XI. . 
XII. 
XIII 
XIV. 
XV. . 
XVI. 
Call to Order and Opening Remarks 3 
Voluntary Compliance 4 
Minutes of March 6-7, 1980 Meeting 12 
Report of Risk Assessment Meeting 12 
Proposed Changes of the Guidelines to Allow Recombinant 
ENA Experiments with Class 3 Organisms and Certain Plant 
Pathogens 14 
Cloning of Foot and Mouth Disease Virus - Stage II 15 
Proposal to Amend Section III-O of the Guidelines to 
Permit Use of Ff Phages 16 
Proposed HV2 Bacillus Subtilis Host- Vector Systems 17 
Proposal to Amend Section III-B-3 of the Guidelines 18 
Proposal to Delete Language Requiring Use of CaMV Mutants 
Lacking the Aphid Transmission Factor from Section III-C-3 of 
the Guidelines; Request for Permission to Transfer ENA 
Fragments from Aphid Transmissible to Aphid Non transmissible CaMV. ..18 
Preposed Revision of Section III-C-1-e of the Guidelines 19 
Proposal to Amend Portions of Section III-A-2-a of the 
Guidelines 20 
Proposal to Amend Section III-C-4 of the Guidelines 21 
Lowering of Containment Levels for Characterized Clones or 
Purified ENAs by IBCs 21 
Proposed Footnote Regarding Variola and Whitepox Virus 22 
Protocols Requiring Assignment of Containment Levels 22 
A. Request for permission to transform Saccharcmycopsis 
lipolytica with Escherichia col i/Saccharomyces cerevisiae 
hybrid plasmids 22 
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