MINUTES OF MEETING - June 5-6 
37 
Dr. Goldstein then moved acceptance of the language at the end of the 
original proposal which read as follows: 
"While the RAC will focus its deliberation on scientific analysis and 
specification of containment (P-LS) procedures at the industrial 
level, we urge: 
1. that enforcement of these containment guidelines be included in 
any regulatory process; 
2. that inclusion of appropriate medical surveillance programs be 
seriously considered." 
Dr. Novick noted that the language singled out industrial applications. 
Dr. Krimsky said that passage of this motion was important in telling 
the regulatory agencies that RAC sees an urgency in this area. 
Dr. Baltimore said he believed NIOSH and OSHA had more important things 
to do than worrying about the potential, very theoretical hazards of 
recombinant DNA. Dr. Campbell said if the regulatory agencies move 
recombinant ENA up on their agenda, something else will be moved back. 
The RAC voted against the proposed language by a vote of four in favor, 
eleven opposed, and three abstentions. 
The language of the proposal to be published in the Federal Register for 
consideration at the September 1980 meeting reads as follows: 
"The following procedures should be adopted for approval of requests to 
grow greater than 10 liters of organisms containing recombinant DNA. 
The RAC will determine if a given recombinant DNA-containing strain 
is rigorously characterized and the absence of harmful sequences 
established. Such a determination shall include specification of a 
containment level (P-LS). These determinations should not in any 
way be construed as RAC certification of safe laboratory procedures 
for industrial scale-up. Adherence to the specified containment 
conditions is the responsibility of the local IBC." 
XXVI. FUTURE MEETING DATES 
The next RAC meeting will be September 25-26, 1980. January 8-9, 1981, 
was tentatively selected as the meeting date for the following RAC meet- 
ing. Mrs. Butler will contact RAC members to arrange meeting dates for 
the rest of 1981. 
XXVII. CLOSED SESSION 
Dr. Setlcw introduced the four large-scale consultants: Dr. Glenwood 
Achom, Higdon, Arkansas; Dr. Elmer Gaden, University of Virginia, 
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