7 
Mr. Thornton called the question on Cr . Gottesman's motion. The RAC 
accepted the language as published in the Federal Register (931/7) by a 
vote of twelve in favor, five opposed, and one abstention. Dr. Goldstein 
requested that his vote of opposed be recorded. Or. Ahmed also requested 
that his vote of opposed be recorded saying he is opposed to a voluntary 
compliance scheme. 
VI. PROPOSED AMENDMENT OF SECTION IV-E-2 
Ms. Cason introduced the proposal (tabs 918, 931/11/A) from Dr. Irving 
Johnson, Eli Lilly and Company, to anend Section IV-E-2 of the Guidelines. 
Ms. Cason recounted the history of the proposal. She noted that several 
proposals to amend the Guidelines were submitted by ft:. Johnson for 
evaluation at the June 5-6, 1980 RAC meeting. Consideration of some of 
these proposals had been deferred. She said ft:. Johnson has resubmitted 
two of those deferred proposals for consideration at the September 6-7, 
1980 meeting. One proposal would insert the following language after the 
first sentence of the second paragraph of IV-E-2: 
"Appropriate representatives of industry shall also be chosen 
to provide expertise in fermentation technology, engineering, 
and other aspects of large-scale production." 
Ms. Cason said that when this proposal was discussed at the June 1980 
meeting, objections were raised to inclusion of the words "of industry." 
A motion recommending the following modified language was passed at the 
June 1980 meeting: 
"Members should be chosen to provide expertise in fermentation 
technology engineering and other aspects of large-scale pro- 
duction." 
She said further discussion of the modified language had been deferred to 
the September 1980 meeting. Ms. Cason said the appointment of a member 
with fermentation technology expertise would afford RAC an additional 
dimension, and moved approval of the modified language. 
Dr. Krimsky asked whether Ms. Cason's proposal might more appropriately 
be evaluated after his proposal to form a subcommittee has been discussed. 
Dr. Gottesman replied that RAC has developed large-scale guidelines and 
would continue to review large-scale applications. Fermentation technology 
expertise would be desirable whether or not a subcommittee as proposed by 
Dr. Krimsky is established. 
Dr. Johnson said he had inserted the words "representatives of industry" 
in his proposal as most expertise in this area is in industry or in 
academia consulting for industry. Dr. Campbell said he did not regard 
himself as a "representative" of academic biology but as an individual 
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