THE JOHNS HOPKINS UNIVERSITY 
SCHOOL OF MEDICINE 
DEPARTMENT OF MICROBIOLOGY 
September 11, 1980 
ns N. WOLFE STREET 
BALTIMORE, MARYLAND SI 105 
Dr. William Gartland 
Chief, Office of Recombinant DNA 
Activities 
National Institutes of Health 
Bldg. 31, Rm. 4A-52 
Bethesda, MD 20205 
Dear Dr. Gartland: 
I have recently learned that Dr. Maxine Singer has 
written to you a letter proposing major changes in the administration 
of the NIH Guidelines for Research Involving Recombinant DNA. I take 
this opportunity to express my strong support for the changes as 
outlined in the Federal Register/Vol. 45, No. 164/Thursday, August 21, 
1980/Notices (page 55926) . These changes would significantly expedite 
recombinant DNA work without altering safety requirements. 
Sincerely yours, 
Hamilton 0. Smith 
HOS :mk 
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