INDUSTRIAL PRACTICES SUBCOMMITTEE 
OF THE FEDERAL INTERAGENCY 
ADVISORY COMMITTEE ON RECOMBINANT 
DNA RESEARCH 
Minutes of First Meeting 
Tuesday, April 1, 1980 
2:00 to 3:30 p.m. 
Room 3025, New Executive Office Building 
Washington, D.C. 
Chairman's Introduction 
Dr. Omenn opened the meeting by reviewing Dr. Fredrickson's 
charge to the Subcommittee in his memorandum of March 12, and 
thanking Drs. Bingham and Robbins for having raised the important 
issue of occupational health attendant upon industrial applications 
of recombinant DNA technology. 
History of Involvement of Industry With the NIH Guidelines 
Dr. Talbot reviewed the involvement of industry with the NIH 
Guidelines, including: 
o Promulgation in January 1980 of a new Part VI of the NIH 
Guidelines entitled "Voluntary Compliance" following endorsement of 
this Part in July 1979 by the Federal Interagency Advisory Committee 
on Recombinant DNA Research, and in September 1979 by the NIH 
Recombinant DNA Advisory Committee (RAC) . 
o Review by the RAC at each of its last three meetings, in 
closed session, of submissions from industry requesting to go over 
10 liters in volume. 
o A recommendation by the RAC at the last meeting that 
Physical Containment Recommendations For Large-Scale Uses of 
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