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DEPARTMENT 
OF HEALTH. EDUCATION. AND WELFARE 
PUBLIC HEALTH SERVICE 
CENTER FOR OISEASE CONTROL 
NATIONAL 
’CP OCCUPATIONAL 
ROCKVILLE. NARV'ANO 2CS57 
Dr. William J. Gartland 
Director, Office of Recombinant DNA Activities 
National Institutes of Health. 
3ethesda, dryland 20205 
Dear 3ill: 
As suggested co us by 3ern±a Talbot, I an formally requesting a 
copy of all submissions nade to the National Institutes of 
Health (NTH) , Office of Recombinant DNA Activities from private 
companies on large-scale (greater chan 10 Hears of culture) 
research or production involving viable organisms containing 
recombinant DNA molecules. 
To assess hazards possibly associated with this new technology, the 
National Institute for Occupational Safety and Health (NIQSH) , must 
be able to evaluate the technical information associated with 
"large-scale" work. The information submitted by industry to NIH is 
a necessary component, together with industrial hygiene surveys and 
control technology assessment, of a hazard evaluation. 
You may wish to advise the private companies that under 29 U.S.C. 6573 
and by virtue of 29 U.S.C. 6693, NIOSH has the authority to request 
information needed to support its research mandate to explore new 
technology for occupational health and safety concerns. NICSH would 
safeguard the submissions as stipulated under 29 U.S.C. 664. 
Your cooperation has aided us in a difficult task and is greatly 
appreciated. 
Sincerely yours, 
Anthony Bobbins, M.D. 
Director 
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