Page 6 of Attachment E 
Section 1 
CONTENTS — PARTI 
Questionnaire sent to various nations and 
page 
organizations and record of responses 
1 
1. Letter and questionnaires 
1 
2. Tabulation of responses 
2 
Section II 
Analysis of Responses to the Questionnaire 
7 
1. Assessment of the adequacy of 
various forms of physical containment 
designs and equipment 
7 
2. Assessment of the adequacy of 
various forms of biological con- 
tainment 
7 
3. Estimates of the frequency of genetic 
exchange in Nature among eukaryotic 
and prokaryotic organisms 
9 
4. Risk assessment experiments 
10 
5. Personnel monitoring 
11 
6. Environmental impact of recombinant 
organisms 
12 
7. Natural history of prokaryotic vectors 
13 
Section III 
Summary of WHO — Sponsored survey of 
individual scientists 
15 
Section IV 
Report on the NIH — Sponsored Risk- 
Assessment Meeting at Falmouth on June 
22, 1977 
16 
Section V 
Comments on other relevant actions, 
reports and meetings 
21 
Section VI 
COGENE — Initiated Risk Assessment 
Analyses ' 
30 
Section VII 
Bibliography and Sources 
34 
Section 1 
CONTENTS — PART II* 
Letters and Documents received in 
Section II 
response to Questionnaire and follow-up 
letter 
(See Tabulation, Section 1, Part 2, for cross 
references) 
Materials received in connection with the 
Section III 
Falmouth Risk Assessment Meeting 
(1) Testimony of Philip Handler, President 
* Part II 
of the U.S. National Academy of 
Sciences, before a U.S. Senate Sub- 
committee Hearing (Nov. 2, 1977) 
(2) Report of a U.S. National Academy of - 
Sciences Panel on Risks and Benefits 
of Recombinant DNA Research Per- 
formed under the NIH Guidelines (Nov. 
1, 1977) 
is available from COGENE (c/o Dr. W.J. Whelan) P.O. 
Box 016129, Miami, FI. 33101, U.S.A. at a cost of $20. 
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