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Page 3 of Attachment H 
Biosafety Committee (IBC) which must have outside membership of at least 
two or twenty percent of the members. Lilly has an IBC of nine members 
of whom three are outside members. I act as chairman. They include the 
Mayor of the 11th largest city in the United States, who is a former 
member of the Congress, and a minister of the Presbyterian Church. 
One could say he represents philosophy and ethics as well as the local 
community while being experienced and familiar with the importance of 
compliance and cooperation with Federal agencies. The other members 
include the Vice President of Indiana University, who is both a physician 
and educator; and a pathologist, expert in diagnosis. He is also Chairman 
of the Infectious Disease Committee of the Indiana University Medical 
r 
School. We have kept the community, our stockholders, and our employees 
informed of our intent and involvement in recombinant DNA research as 
described in congressional testimony (1,2). 
In considering potential occupational hazards in this area I will 
comment, on five principle items. These are: 
(1) The origin of the 10-liter (10L) limitation. 
(2) The safety of E_. col i K12 as determined by recent risk 
assessment programs. 
(3) The reliability and operating procedures of commercial scale 
fermentation equipment including training of operators. 
(4) Medical surveillance program for equipment operators. 
(5) The current authority of OSHA and the FDA. 
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