Page 13 of Attachment B 
Features of Contained Fermentor 
Eli Lilly 2,000 Liter Fermentor 
Second 
Back Up 
Sterile Filter 
Exhaust Gas 
Filter System (1) 
Compressed Air 
Inlet 
Other Features 
(6) Collection of 
Contaminated 
Condensate and 
Sterilization before 
Release 
(7) System Validation 
before Operation 
(8) Monitoring Program 
(9) Operation with 
Detailed Protocol 
Special Double Mechanical 
Seal with Sterile Fluid Purge 
(2) and Loss of Pressure Alarn 
Dip Tube 
Harvest & F 
Line (3) 
Stainless Steel 
Steriiizable 
Sampler (4) 
Cooling Jacket 
Agitator 
Air Sparger 
Submitted by the Eli Lilly Co. 
[513] 
