Page 1 of Attachment D 
EXECUTIVE OFFICE OF THE PRESIDENT 
OFFICE OF MANAGEMENT AND BUDGET 
WASHINGTON. D.C. 20503 
September 23, 1980 
MEMORANDUM FOR: DR. DONALD S. FREDERICKSON 
DIRECTOR, NATIONAL INSTITUTES OF HEALTH 
This memorandum constitutes an interim report from the Industrial 
Practices Subcommittee of the Federal Interagency Advisory 
Committee on Recombinant DNA Research, to you, as Chairman of 
the parent committee. 
Our subcommittee has now met three times — April 1, June 18, 
and September 4, 1980. Appended are the minutes of these three 
meetings. As you can see from the minutes, we have had detailed 
presentations from the National Institutes of Health, Occupational 
Safety and Health Administration, National Institute of Occupational 
Safety and Health, Food and Drug Administration, Environmental 
Protection Agency, Department of Commerce, Department of Agriculture, 
and the Office of Technology Assessment. In addition, we heard 
presentations from invited representatives of the American Federation 
of Labor and Congress of Industrial Organizations, Oil, Chemical 
and Atomic Workers International Union, Pharmaceutical Manufacturers 
Association, and Eli Lilly and Company. 
We are closely monitoring developments, such as: 
The results of NIOSH site visits to industry and its 
development of recommendations on worker education 
and medical surveillance; 
The deliberations of the NIH Recombinant DNA Advisory 
Committee on possible changes in its procedures for 
reviewing over-10-liter submissions ; 
EPA risk assessment studies; 
FDA's preparations to review submissions involving 
products made with recombinant DNA techniques; 
OTA's study "Impacts of Applied Genetics." 
FROM: 
Dr. Gilbert S. Omenn 
Chairman, Subcommittee u.. uie Federal 
Interagency Advisory Committee on 
Recombinant DNA Research 
SUBJECT: 
Interim Report of the Industrial Practices 
Subcommittee of the Federal Interagency 
Advisory Committee on Recombinant DNA 
Research 
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