-5- 
Attachment III - Page 5 
2. Written consideration of question should not be required. 
Singer 
Confusing — just note similarities and differences. 
Juengst 
3. Is investigator a soothsayer? Several aspects are political 
and therefore contentious and trouble spots. 
Singe r 
Integrate questions at other points in the document. 
Juengst 
This section pertains to general vs. the case approach and 
should be considered by public before the therapy is 
undertaken. Since the RAC doesn't seem to have a position 
on the positive and negative aspects of gene therapy, it is 
hard to review protocols. The document fails to answer the 
President's Commission's report on gene splicing that you 
were formed to answer. 
Cavalieri 
Part III 
F and G request the same information. 
McKinney 
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