Tab C - Page 23 
THl: UNIVERSITY OF NORTH CAROLINA 
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May 16, 1985 
Dr. William J. Gartland 
ORDA 
Building 31, Room 3B10 
National Institutes of Health 
Bethesda, Maryland 20205 
Dear Dr. Gartland: 
I write as the President of the Association of Medical School 
Departments of Biochemistry to state that as the principal elected repre- 
sentative of my society, I believe I can give their general support for 
the Lindow and Panopoulous field test of ice-nucleation-minus bacteria 
prepared by recombinant DNA techniques. 
I have read the NIH Environmental Assessment, the Federal Register, 
Vol. 50, No. 72, p. 455-456 (1985) and the text of a letter from the American 
Society of Microbiology Public and Scientific Affairs Board in response to 
the Federal Register Notice. 
I believe the most crucial issue is that natural deletion mutants occur 
so that the recombinant deletion mutants cannot be considered unique. It is 
the process that produced the recombinant mutants that is unique. However, 
in addition, I believe the Environmental Assessment was exhaustive. 
It is hard to alert all of the members of my Association which represents 
about 130 medical school biochemistry departments, but I am sure my view would 
represent a majority of the members if they had the information I do. 
Sincere ly 
Kenan Professor and Chair 
MEJrlmh 
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