'The object of these guidelines is to ensure that experimental DNA 
recombination will have no ill effects on those engaged in the work, on the 
general public, or on the environment. ... It should be noted that the 
development of the guidelines was in large part tantamount to conducting 
an environmental impact assessment. For example, the objectives of 
recombinant DNA research and alternate approaches to reach these 
objectives, have been considered. The potential hazards and risks have 
been analyzed. Alternative approaches have been thoroughly considered to 
maximize safety and minimize potential risk. And an elaborate review 
structure has been created to achieve these safety objectives." 
The NIH published a Draft Environmental Impact Statement on the Guidelines in 
the Federal Register for public comment on September 9, 1976. After analysis of 
the comments received a final Environmental Impact Statement (EIS) on NIH 
Guidelines for Research Involving Recombinant DNA Molecules was published in 
October 1977. 
Environmental Assessment 
Paee 4 
[ 474 ] 
