The original submission of May 5 , 1983, by Cetus Madison Corporation (CMC) to 
the NIH, requested approval under Appendix L of the Guidelines to field test 
cotton, soybean, corn, tobacco, tomato and potato, grown from seeds containing 
recombinant DNA. Following the RAC Plant Working Group's review of the 
original submission and additional information supplied by CMC, a letter of July 1, 
1983, from Dr. William Gartland, Director, NIH Office of Recombinant DNA 
Activities, to Dr. Winston Brill, Director of Research, CMC, indicated the 
decision that the submission did not meet the criteria required for approval under 
Appendix L of the Guidelines, and would therefore require review not only by the 
RAC Plant Working Group but also by the full RAC. 
On July 1, 1983, Dr. Brill submitted a revised proposal to field test cotton, 
tobacco and tomato, grown from seeds containing recombinant DNA. After 
review by the RAC Plant Working Group, a letter of July 26, 1983, from 
Dr. Gartland to Dr. Brill requested additional information. 
On August 19, 1983, Dr. Brill submitted a revised proposal "to field test tobacco, 
cotton, and tomato that have been genetically engineered for resistance to the 
disease, crown gall." The proposal was reviewed by the RAC Plant Working Group 
on September 7, 1983 and by the full RAC on September 19, 1983. At its 
September 19, 1983 meeting, the RAC passed the following motion by a vote of 12 
in favor, 1 opposed: 
Environmental Assessment 
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