"The proposal by Cetus Madison to field test genetically engineered 
tobacco, cotton, and tomato plants, as described in their August 19, 1983, 
submission, was considered by RAC and, while acceptable in principle, 
requires further amplification and clarification before approval. RAC will 
empower the Plant Working Group to review and approve this proposal 
after further consideration of specific planting and monitoring procedures 
for the engineered tobacco plants and the results of greenhouse tests for 
engineered cotton and tomato plants." 
On October 21, 1983, Dr. Brill wrote giving "further data on the field design and 
the types of observations to be made," and also limiting the request to tobacco. 
On December 21, 1983, the RAC Plant Working Group unanimously recommended 
approval of the request as described in the submissions from Cetus Madison 
Corporation of August 19, 1983, and October 21, 1983. 
On January 24, 1984, the U.S. Department of Agriculture Recombinant DNA 
Committee (ARAC) unanimously concurred with the recommendation of the NIH 
RAC Plant Working Group. 
On March 15, 1984, Dr. Gartland wrote to Dr. Brill indicating an NIH decision that 
the -proposal shpuld be reviewed once more by the full RAC. 
On April 13, 1984, Dr. Brill resubmitted the request consisting of the same 
material previously submitted on August 19, 1983, and October 21, 1983. 
Environmental Assessment 
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