17 
Dr. Dean said the rationale for restricting plasmids whose host-range includes 
B. cereus was that some Eh_ cereus strains produce an errterotoxic food toxin. 
On the basis of exceptional B^_ cereus strains, all plasmids which can be intro- 
duced into B^ cereus were eliminated from use under Appendix C-IV. 
The working group supported this proposal and agreed to offer it as a recormen- 
dation to RAC. 
Dr. Friedman adjourned the meeting of the Working Group on Gram Positive Bacteria 
at 3:05 p.m. on December 2, 1985. 
[Executive Secretary's Note: The proposal offered by Drs. Novick and Polak cite 
references which support the working group reccrrmendat ion . The working group 
in addition has compiled a reference list supporting its recommendation. That 
reference list is appended to these minutes as Attachment V.] 
Respectfully submitted. 
Eliza]6£th A. Milewski, Ph.D. 
Executive Secretary 
H i 
I herdoy certify that, to the best 
of my knowledge, the foregoing 
Minutes and Attachments are accurate 
and complete. 
$ /A AjmJ 
David I. Friedman, Fh.D. 
Chair 
Working Group on Viruses 
[548] 
