18 
or worked with. In addition, the CDC (as well as the Department 
. 
of Transportation) has the authority to regulate the interstate 
shipment of etiologic agents. 
4. National Institute of Occupational Safety and Health (NIOSH) : 
NIOSH is one of the seven operating divisions of. CDC. Part of 
the NIOSH program, addressing potential hazards to workers 
related to commercial biotechnology, included on-site surveys of 
companies moving into scale-up or pilot production phases of 
operation. Initial walk-through surveys were conducted at rDNA 
facilities located at Eli Lilly, Genetech, Burns-Biotec and 
Cetus to assess the control measures and reduce human exposures. 
Information ob- tained from this program could be used to 
develop methods to minimize identifiable risks to workers and to 
advance recommenda- tions to specific companies. Topics that 
will be covered by the program include: 
o Physical containment design (e.g., fermenters) 
o Engineering controls (e.g.,. ventilation, exhaust gas 
filtration) 
o Work practices (e.g., operational protocols, clothing, 
and hygiene requirements) 
o Validation procedures (e.g., sterilization and fermenter 
containment) 
o Emergency procedures (e.g., spills) 
o Environmental monitoring 
[619] 
