May 21-23 - MINUTES OF MEETING 
2 
Other National Institutes of Health staff present were: 
Dr. Stanley Barban, NIGMS; Dr. Emmett Barkley, NCI; Mrs. Betty Butler, 
NICMS; Dr. John Irwin, DRS; Dr. Richard Krause, NIAID; Dr. Malcolm 
Martin, NIAID; Dr. John Nutter, NIAID; Dr. Michael Resnick, NIGMS; 
Dr. John Seal, NIAID; Dr. Bernard Talbot, OD; and Dr. Rudolph Wanner, DRS. 
Others in attendance for all or part of the meeting were : 
Dr. Richard Axel, Columbia University; Mr. A. Botlin, Becton-Dickinson & Co.; 
Dr. Philip Bereano, University of Washington; Dr. Liebe F. Cavalieri, Sloan- 
Kettering; Mr. Jeffrey Christy, Blue Sheet; Mr. David Dickson, Nature; 
Mr. Leslie Dach, Environmental Defense Fund; Mr. Mark Finkelstein, Schering 
Corporation; Mrs. Robin M. Henig, BioScience Magazine; Dr. Paul Hung, 
Abbott Laboratories; Dr. Jonathan King, Massachusetts Institute of Technology; 
Dr. Manried Koch, Federal Republic of Germany; Dr. Paul Leibowitz, Schering 
Corporation; Mr. Max M. Marsh, Lilly Research Laboratories; Dr. James M. 
McCullough, National Library of Congress; Dr. Beatrice Mintz, Institute 
for Cancer Research, Philadelphia; Mr. Stuart Neuman, SUNY/Albany; 
Mr. Ronald L. Phillips, USDA-Canpetitive Grants; Mr. Richard Silon, Food 
and Drug Administration; Ms. Francine Simring, Coalition for Responsible 
Genetic Research; Mr. Louis Slesin, Natural Resources Defense Council; 
Mr. Dan Smith, People's Business Ccmmission; and Dr. Susan Wright, University 
of Michigan. 
I. CALL TO ORDER AND OPENING REMARKS 
Dr. Jane Setlow, Chairman, called the meeting to order at 9 a.m. , May 21, 
1979. Dr. Setlow announced that Drs. Kutter, Redford, Rowe, and Spizizen 
vould be leaving the RAC on June 30 as their appointments expire. In 
addition, Drs. Day and Homick will resign due to the assumption of new 
responsibilities. Dr. Setlow noted that Dr. Rowe had been awarded the 
Paul Ehrlich and Ludwig Darmstaedter Prize for 1979. 
II. Containment Levels for Experiments Involving Actinomycetes 
Dr. Julian Davies, an ad hoc consultant, introduced this proposal (672) 
which was published for comment in the April 13, 1979 Federal Register as 
follows: 
"P2 physical containment shall be used for DNA 
recombinants produced between members of the 
Actinomycetes group except for those species 
which are known to be pathogenic for man, 
animals or plants. [2A]" 
