May 21-23 - MINUTES OF MEETING 
4 
"P2 physical containment shall be used for DNA 
recombinants produced between members of the 
genera Streptomyces and Micromonospora except 
for those species which are known to be 
pathogenic for man, animals or plants [2A] 
After the vote, Dr. Day moved to accept the following proposal: 
"P2 physical containment shall be used for DNA 
recombinants produced between members of the 
genera Streptomyces and Micromonospora except 
for those species which are known to be patho- 
genic for animals." 
Dr. Day stated that it was the intent of his motion to allow important 
work on plant pathogens under P2 conditions, which he feels is adequate. 
It was agreed that the entire issue of containment for plant pathogens 
needs further study and discussion. Dr. Day agreed and requested that 
no vote be taken on his motion. Prior to the next meeting, the Executive 
Secretary will redistribute to the RAC the report of the 1978 Workshop 
on Risk Assessment of Agriculture Pathogens. 
III. EXEMPTION FOR STREPTOMYCES SPECIES THAT EXCHANGE GENETIC 
INFORMATION 
The Working Group on Prokaryotic Host-Vectors other than E. coli recom- 
mended that a list of Streptomyces species that have been shown to 
exchange chrcmoscmal DNA be placed in the exemption category of Section 
I-E-4. This proposal was published in the Federal Register on April 13, 
1979 as follows: 
" Streptomyces species that have been shown to exchange 
chromosomal DNA are proposed to be included under the 
exemption category of Section I-E-4 of the 1978 Guide- 
lines. Any recombinant DNA molecules that are composed 
entirely of DNA segments from one or more of the organ- 
isms listed below and to be propagated in any of the 
organisms listed below are exempt from the Guidelines. 
(This list is to be separate from the other lists of 
exempt organisms in Appendix A.) 
Streptomyces aureofaciens 
Streptomyces rimosus 
Streptomyces coel icolor 
[ 99 ] 
