May 21-23 - MINUTES OF NESTING 
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active molecules appears low enough not to preclude 
lowering of containment. This conclusion is based 
on the following considerations:" 
Sane minor modifications in the report were approved as follows: 
Section l.(iii) - "will" is to be changed to 
"should." 
Section l.(iv) - Certified hosts containing 
these clones "should not establish" instead 
of "will not establish;" deletion of last- 
sentence beginning with "such hosts." 
Section 1. - At the end of Section 1, a new 
sentence is to be added that reads: "Further 
studies on autoimmunity will be undertaken." 
Section 2 - The first sentence is modified to 
read: "cDNA made from a single mRNA of known 
function is considered characterized by 
definition." The RAC accepted this recommendation 
by a vote of 15 to 1. The word "appendix" is 
changed to "footnote." 
section 3 - The RAC voted to accept this 
section by a vote of 15 to 0, with 2 abstentions, 
after the change of "gene" to "gene(s)." 
section 4 - The last sentence was changed to 
read "Containment shall be no less than the com- 
ponent characterized clone with the highest 
containment. " The RAC voted to accept this 
version of this section by a vote of 17 to 0, 
with 1 abstention. 
Dr. Day proposed a new preamble for the 
recammendat ions . 
The final report which was passed by a vote of 17 in favor, 1 opposed, 
appears in Attachment VI. 
XIV. DEFINITION OF EKl 
The RAC discussed amendment of Section II-D-l-a-(l) of the Guidelines. 
The proposed amendment would read as follows: 
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