May 21-23 - MINUTES OF MEETING 
30 
The RAC agreed that the first part of the experiments, 
i.e., the formation and propagation in EN coli K-12 of the 
recombinant molecules, is explicitly covered by the 
Guidelines, and requires P2 + EK1CV containment. 
The second set of experiments is designed to study trans- 
formation of susceptible cells and will not result in the 
production of infectious viral particles. Analogous experiments 
linking SV4u DNA or retrovirus genes with the thymidine 
xinase gene of herpes simplex virus have already been 
approved at P2 containment by the NIH. Dr. Baltimore's 
motion recommending P2 containment for the insertion of 
the recombinant plasmids into human cells was carried by a 
vote or 13 in favor, 1 opposed, with 6 abstentions. 
XXVI 1. FUTURE MELTING DATES 
The RAC selected the following dates for future meetings: 
September 6-7, 1979 
December 6-7, 1979 
March 6-7, 1980 
XXVI 1 I . ADJOURNMENT 
The meeting was adjourned at 12 noon, May 23, 1979. 
Respectfully submitted. 
William J. Garfland, Jr., Ph.D. 
Executive Secretary 
[ 125 ] 
