2 
Dr. Gartland summarized the two meetings of the RAC held since 
the implementation of the revised Guidelines. At those meetings, in 
February and May, actions were taken regarding approval of host-vector 
systems, exemptions from the Guidelines, containment levels for specific 
experiments, and plans for a risk-assessment program. Dr. Gartland 
commented that the Guideline procedures seem to be working effectively 
in the operations of ORDA and the RAC and the publication of various 
actions in the Federal Register . 
Dr. Gartland also reported that, concomitant with the implementation 
of the revised Guidelines, 8 members were added to the RAC to meet the 
charter requirement of up-to-25 (including at least 8 who are knowledge- 
able in molecular biology or recombinant DNA, 6 who are not in those 
fields, and 6 who are in specified fields relevant to the subject). 
Dr. Gartland remarked that the expanded group has worked well. Then he 
provided a list of all the Federal agencies that have appointed liaison 
members to the RAC (Attachment B), noting that some agencies have yet 
to name representatives. Dr. Fredrickson urged the agencies that have 
not named representatives to do so as soon as possible. Finally, 
Dr. Gartland reported on a Board of Scientific Counselors (Attachment C) 
consisting of representatives from research agencies significantly in- 
volved in recombinant DNA activities. 
Dr. Fredrickson asked how Federal agency representation is faring 
under the Guideline arrangements. All of the agencies on the Board of 
Scientific Counselors reported that the procedures have served well in 
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