NINETY-SIXTH CONGRESS 
ROOM 2415 
RAYBURN HOUSE OFFICE BUILDING 
PHONE (202) 225-4952 
HENRY A. WAX MAH. CALIF.. CHAIRMAN 
DAVID e. SATTERFIELD III. VA. 
RICHARDSON PRCYER. N.C. 
ANDREW MAGUIRE. N.J. 
THOMAS A. LLTKEN, OHIO 
DOUG WALGREN. PA. 
BARBARA A. MIKUL5KI. MD. 
PHIL GRAMM. TEX. 
MICKEY LELANO. TEX. 
RICHARD C. SHELBY. ALA. 
JOHN M. MURPHY. N.V. 
HARLEY O. STAGGERS. W. VA. 
(ex officio) 
TIM LEE CARTER. KY. 
SAMUEL L. DEVINE. OHIO 
DAVE STOCKMAN. MICH. 
WILLIAM E. OANNEMEYER. CALIF. 
GARY A. LEE, N.Y. 
JAMES T. RROYHIUL. N.C. 
(ex officio) 
Congress of tfce ©ntteb Stated 
House of JUpresfentattoe* 
Subcommittee on fttaltb anb tfjt Cnbironmmt 
o( rtje 
Committee on interstate anb foreign Commerce 
Wafibington, 3B.C. 20515 
October 11, 1979 
Dr. Donald Fredrickson 
Director 
National Institutes of Health 
Building 1, Room 124 
Bethesda, Maryland 20205 
Dear Dr. Fredrickson: 
I have had a continuing interest in the guidelines govern- 
ing the conduct of recombinant DNA research. I was concerned, 
therefore, to learn that the National Institutes of Health Re- 
combinant DNA Advisory Committee suggested significant changes 
in the conditions required for experiments using E. coli K-12. 
I would like to have more information on this matter. In 
this regard, I would appreciate being informed of the new scien- 
tific information or other data which led to the Advisory Commit- 
tee's decision. Further, I understand the Advisory Committee 
passed the motion suggesting a change in the containment require- 
ments for E. coli K-12 experiments with less than a 50% majority 
of the Committee membership voting in the affirmative. Could you 
let me know if all Committee members were notified prior to the 
meeting that this matter would be discussed and there would be a 
vote on this motion. 
I will look forward to your immediate review and response. 
It would be helpful also if you could enclose a copy of the rules 
governing the advisory bodies conduct of business. If you have 
any questions, please feel free to contact me or Dr. Martin 
Kagnoff of my staff at 225-3976. With kindest regards. 
Sincerely, 
a — 
WAXMflW 
Chairman 
HAWrmkm 
1 
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