MINUTES OF MEETING - December 6-7, 1980 
3 
I. CALL TO ORDER AND OPENING REMARKS 
Dr. Jane Setlcw, chairperson, called the meeting to order at 
9 a.m. , December 6, 1979. Dr. Setlcw began the meeting by intro- 
ducing a new Recombinant DNA Advisory Committee (RAC) member, 
Dr. Jean Harris. She also introduced two ad hoc consultants. 
Dr. Roger Herriott and Dr. Kenneth Bems. 
II. MINUTES OF SEPTEMBER 6-7, 1979 MEETING 
The RAC reviewed the minutes of the previous meeting (tab 795). 
Dr. Walters said that he had discovered one substantive error 
which he believed to be typographical; on page 35 in line 19: 
"Section le" should be "Section lc." He added that he had some 
minor editorial suggestions to submit to the Executive Secretary. 
Dr. Walters then moved approval of the Minutes. Dr. Ahmed noted 
that in the vote on the EL coli K-12 proposal several individuals 
had requested that their vote be recorded; those names had not 
been included in the Minutes. Dr. Ahmed added that the names of 
people assigned to working groups should be recorded in the 
Minutes. Dr. Wright, a member of the public, said that in the 
previous meeting she had questioned Dr. FYed rick son regarding 
NIH's position on mandatory regulation of industry, and that 
neither her question nor his response had been included in the 
Minutes. She requested that this exchange be included. With 
incorporation of these changes, the Minutes were approved 
by a vote of fourteen for, none opposed, with one abstention 
(Ms. King). 
III. STATUS OF RAC RECOMMENDATIONS MADE AT SEPTEMBER 1979 MEETING 
Dr. Setlcw delivered an update on the the status of the major 
actions recommended by the RAC at the September 1979 meeting. 
She stated that tab 796 is the text of a notice that appeared 
in the Federal Register on November 30, 1979. The notice 
publishes for 30 days of comment the proposed revised Guidelines 
incorporating actions recommended at the September 1979 meeting. 
Following this comment period, a final decision on these actions 
will be published. 
Dr. Setlcw noted that Dr. Fredrickson's proposed decision departs 
somewhat from the E. coli K-12 proposal as recommended by the 
RAC in September. In Dr. Fredrickson's proposal, most EL coli 
K-12 manipulations are not exempt from the Guidelines; registra- 
tion and review by NIH would not, however, be necessary for these 
experiments. She noted that Dr. Fredrickson accepted PI + EK1 
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