THE UNIVERSITY OF CHICAGO 
DEPARTMENT OF BIOPHYSICS AND THEORETICAL BIOLOGY 
Dr. Donald S. Fredrickson, Director 
National Institutes of Health 
Bethesda, MD 20205 
Dear Dr. Fredrickson: 
I strongly support the revisions of the Recombinant DNA Guidelines 
as published in the Federal Register for November 30, 1979* In 
particular, I agree with the revisions embodied in Section III-O 
(p. 69218) which reduce the registration and containment require- 
ments for experiments using E. coli K-12. It is regrettable that 
these revisions have been delayed for further comment in view of 
the extensive period provided already for such comments and the 
existensive discussions by the Recombinant DNA Advisory Committee 
prior to its votes. I believe that the expense in terms of time 
taken from other fruitful activities of yourself and the many com- 
mentators on this issue was unnecessary and extremely wasteful. 
CUMMINGS LIFE SCIENCE CENTER 
920 EAST S8TH STREET 
CHICAGO • ILLINOIS 60637 
December 11, 1979 
Sincerely yours 
Robert Haselkorn 
F. L. Pritzker Professor 
and Chairman 
RH:ap 
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