Microbiology Department 
Brigham Young University 
December 14, 1979 
Director 
NIH 
Bethesda, MD 20205 
Attention: Dr. Fredrickson 
Dear Sir: 
I support the downgrading of the containment requirements 
regarding _E. coli K-12 host-vector systems (Federal Register, 
Nov. 30, 1979, section III-O) to a PI facility for those 
experiments noted in the above publication. 
Sincerely 
Associate Professor of Microbiology 
sb 
[ 480 ] 
775 WIDB, Brigham Young University, Provo, Utah 84602 (801) 374-1211, Extension 2889 
