MICROBIOLOGY 
December 14, 1979 
Donald S. Fredickson, Director 
National Institutes of Health 
Bethesda, Maryland 20014 
Dear Dr. Fredrickson: 
I support the recommendation concerning E. col i K12/P1 published 
in Federal Register 44 ( 232 ) : 69234 , November 3tf, 1 979. 
The use of £. coli K12 strains in recombinant DNA experiments 
provides no risks to the researchers and passage of the recommendation 
would greatly facilitate work in this field. 
Sincerely, 
l(Lu. i 
iathan W. Uhr, M.D. 
Professor and Chairman 
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5323 MARRY HINES BLVO DALLAS. TEXAS 75235 (214)688-2555 
