MEMORIAL SLOAN-KETTERING GANGER CENTER 
1273 YORK AVENUE. NEW YORK. NEW YORK 10021 
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m • 
*. O 
December 17, 1979 
Donald S, Fredrickson 
Director, National Institutes of Health 
Bethesda, MD 20205 
Dear Dr. Fredrickson: 
I strongly urge the adoption of the proposed Recombinant DNA 
Guidelines set forth in the Federal Register, Vol, 44, No. 232, 
Nov. 30, 1979. I am most enthusiastic about the E. coli K-12/P1 
recommendation which embodies a realistic assessment of several 
years' experience with this system as well as direct tests of its 
safety. Adoption of the Revised Guidelines will greatly facilitate 
my studies on retrovirus RNA synthesis. 
Yours truly. 
ES : ale 
Edward Stavnezer, Ph.D. 
Associate, Sloan-Kettering Institute 
for Cancer Research. 
[519] 
MEMORIAL HOSPITAL FOR CANCER AND ALLIED DISEASES 
SLOAN KETTERING INSTITUTE FOR CANCER RESEARCH 
SLOAN KETTERING DIVISION. GRADUATE SCHOOL OF MEDICAL SCIENCES. CORNELL UNIVERSITY 
