MEMORIAL SLOAN-KETTERING GANGER CENTER 
Dr. Donald S. Fredrickson, Director 
National Institutes of Health 
Bethesda, MD 20205 
Dear Dr. Fredrickson: 
I am writing to express my support for the proposed Revised 
Guidelines for Research Involving Recombinant DNA Molecules. To 
those of us working on the molecular biology of cancer it is evident 
that recombinant DNA methods have added great impetus to the broad 
range of research aimed at understanding the basic mechanisms of gene 
action in mammalian cells. The new classification of E. coli K- 1 2 
host-vector systems in the proposed guidelines (Section III-O) will 
permit more rapid application of new information, without compromising 
the scientific and administrative rigor of the present review system. 
I am convinced that this adjustment in the guidelines will permit 
a more rapid realization of the goals of the national cancer program. 
1275 YORK AVENUE. NEW YORK, NEW YORK 10021 
December 18, 1979 
Yours sincerely 
EF:aic 
Erwin Fleissner, Ph.D. 
Head, Laboratory of Viral Oncology 
Coordinator, Field of Oncogenic Virus 
Research. 
[524] 
MEMORIAL HOSPITAL FOR CANCER AND ALLIED DISEASES 
SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH 
SLOAN-KETTERING DIVISION, GRADUATE SCHOOL OF MEDICAL SCIENCES, CORNELL UNIVERSITY 
