HARVARD UNIVERSITY 
The Biological Laboratories 
Department of Biochemistry and Molecular Biology 
16 Divinity Avenue 
Cambridge, Massachusetts 02138 
19 December 1979 
Dr. Donald Frederickson 
Director 
National Institutes of Health 
Bethesda, MD 20205 
Dear Dr. Frederickson, 
I urge enactment of the new recombinant 
DNA guidelines as proposed in the Federal Register 
Volume 44, No. 232, Friday, 30 November 1979, 
pp. 68210-69251. 
Sincerely yours, 
W\. W 
Matthew Meselson 
Professor of Biochemistry 
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