MEMORIAL SLOAN-KETTERING GANGER CENTER 
Dr. Donald Frederickson 
Director, National Institutes of Health 
Bethesda, Maryland 20205 
Dear Dr. Frederickson: 
I am writing to comment on the proposed revised recombinant DNA guidelines, 
published in the Federal Register on November 30, 1979. 
I believe, in light of the evidence obtained to date concerning the 
potential dangers of this work, that the revised guidelines are quite 
reasonable. They strike a fair balance by continuing safety precautions 
for work of this sort, without imposing excessive restrictions which in the 
past have tended to slow the progress of this most important area of 
research. The abolishment of the MUA is an excellent idea, since this 
requirement has in the past generated a great deal of paperwork ^nd time 
both for the research institutions and for the NIH. 
As someone who is involved in recombinant DNA research, I thus hope 
that you will approve the revised guidelines. 
1275 YORK AVENUE, NEW YORK, NEW YORK 10021 
December 19, 1979 
Associate Member 
CB/v 
[544] 
MEMORIAL HOSPITAL FOR CANCER AND ALLIED DISEASES 
SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH 
SLOAN-KETTERING DIVISION, GRADUATE SCHOOL OF MEDICAL SCIENCES, CORNELL UNIVERSITY 
