CARNEGIE INSTITUTION OF WASHINGTON 
Department of Embryology 
115 West University Parkway 
Baltimore. Maryland 21210 
TELEPHONE: 467-1414 
December 19, 1979 
Dr. Donald Fredrickson, Director 
National Institutes of Health 
Building 1 - Room 124 
Bethesda, Maryland 20205 
Dear Dr. Fredrickson: 
I fully support the Recombinant DNA Advisory Committees' recommendation 
to downgrade work with col i K12 and non-transmissible plasmids to PI 
status. The accumulated experience in this area fully warrants this change 
in status. 
Sincerely, 
Nina Fedoroff 
NF:ps 
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