UNIVERSITY OF CALIFORNIA. SAN DIEGO 
BERKELEY • DAVIS • IBVTSE • LOS ANGELES • RIVERSIDE • SAN DIEGO • SAN FHANOSCO 
SANTA BARBARA • SANTA CHITZ 
DEPARTMENT OF BIOLOGY. C-016 
LA JOLLA. CALIFORNLA 92093 
Decer-oer 2 ! , 1979 
Dr. Donald Fredrickson, Director 
‘National Insti+ues of Health 
Bethesda, Maryland 20205 
Dear Dr. Fredrickson: 
This is to express ny opinion that the new modified 
^owe-Ca'-'pbe I I a~endrent to tre recombinant D‘«A guide- 
lines is a rational, reasonable a^nd-ent. 
It is in the best interests of American science 
and the public interest that these be adopted. I 
endorse them without reservation. 
Sincerely 
Jobr Hoi I and 
D rofessor of Biology 
/Is 
[ 565 ] 
