December 23, 1979 
Or. D. Frebricksdn, Directbr 
NIH 
Be the* da, Mb. 20205 
Dear Dr. Frebicksbn, 
I WBULB LIKE TB BTRBNBLV ENBBRSE VDUR RELAXATIBN 
BF THE NIH BUI BEEINEB IN THE FBRM BF THE CLASS 
BF EXFERIMENT8 AS PUBLISHED IN THE FEBERAL RESISTER 44 
(1979), f. 69210. Fsr the last 5 years I have seen 
A8SBC | ATED'WTH RECBMBINANT DNA RESEARCH WBRKINB AS A 
DISHWASHER ANS STUDENT HELP IN THE DEPARTMENT BF QENETICS 
BF THE UNIVERSITY BF WISCBN8IN. I HAVE HAD A CHANCE 
TB SEE MANY BF THE UNNECESSARY RESULATISN6 IN ACTIBN 
AND THE ACTUAL DAMAQS8 CAUSED BY THEM. FDR IN8TANCE 
THE EXCE86IVE AUTBCLAVINQ DEMANSED SY THE QU I DELINES IS 
DANBERBUS TB THBSE BF US WHS HAVE TB DB IT AND INCREASES 
THE RISK BF BURN8 AND BTHER UNNECESSARY INWURIE8. DlO 
YBU CBNSIOER US AND BUR HEALTH WHEN PRBMBTINB THE8E 
RULE8 AND RESULATIDNS? 
Sincerely yburs, 
Barbara Szysalski 
Department bf Genetics 
University bf Wiscbnsin 
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