THE UNIVERSITY OF CHICAGO 
DEPARTMENT OF BIOCHEMISTRY 
920 EAST 5 8 T H STREET 
CHICAGO • ILLINOIS 60637 
December 24, 1979 
Dr. Donald S. Frederickson 
Director 
National Institutes of Health 
Bethesda, Maryland 20205 
Dear Sir: 
I am writing to express my vigorous support in favor of the adoption 
of the revised NEH Guidelines for Recombinant DNA Research as published 
in the Federal Register (11/30/79). I believe that recombinant DNA 
research over the past five years coupled with recent findings such as 
the discovery of discontinuous eukaryotic genes now render the probability 
for creation of new pathogenic strains of bacteria several orders of 
magnitude lower than previously estimated. On the other hand, the 
technology has become indispensable for molecular genetics and has shown 
increased potential for practical applications. 
Sincerely 
< 
Research Associate 
SJC:aj 
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