UNIVERSITY OF COLORADO 
MEDICAL center 
4200 CAST NINTH AVENUE 
DENVER COLORADO 00262 
or M I CAO I 3LOSI and immumoiocv 
December 26, 1979 
t|lD»mohi 
> 03 ' 3 > 4-7003 
Dr. Donald S. Fredrickson 
Director, National Institutes of Health 
Bethesda, Maryland 20205 
Dear Dr. Fredrickson: 
I have carefully read and considered the arguments for and 
against altering the NIH Guidelines for Recombinant DNA Research, 
as they appear in the Federal Register, Vol . 44, No. 232, Nov. 30, 
1979. I am very much impressed by the thoroughness of the 
Recombinant DNA Advisory Committee’s work and I am essentially in 
agreement with their major col i K-12/P1 Recoimendation" . As 
a long-time £. col i geneticist and occasional user of recombinant 
DNA technology, I feel that I can make an objective evaluation 
of their recommendation. 
I think that your Proposed Decision on this recommendation, as 
specified in Section III-E of your report, is appropriate in all 
respects. I agree that there should be no blanket exemption of 
all £. col i K-12/P1 experiments and that local IBCs should take 
on the major responsibility for reviewing registered proposals 
of this type and for determining that the requirements of the 
Guidelines are met. The purpose of this letter, therefore, is to 
indicate my full support for your Proposed Decision. 
Yours sincerely 
Austin L. Taylori^ Ph.D. 
Associate Professor of 
Microbiology/ Immunology 
School of Medicine 
ALT/vet 
[597] 
THE UNIVCRS TY OF COLORADO »S AN EQUAL OPPORTUNITY EMPLOYER 
