STANFORD UNIVERSITY MEDICAL CENTER 
DEPARTMENT OF GENETICS 
December 26, 1979 
Dr. Donald Fredrickson 
Director, National Inst, of Health 
Bethesda, Maryland 20013 
Dear Dr. Fredrickson, 
I strongly support the approval of the version modified and 
approved by you regarding: 1) much of the cloning in JE. col i K-12 
be exempt from NIH guidelines and 2) Pi containment would be 
sufficient. It is however important that any of these type of 
experiments must be registered with the Institutional Biosafety Com- 
mittee prior to the initiation of the experiment. 
A.T. Ganesan 
Professor 
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DEPARTMENT OF GENETICS, STANFORD UNIVERSITY SCHOOL OF MEDICINE, STANFORD, CALIFORNIA 94305 • (415) 497-5052 
