ROSWELL PARK MEMORIAL INSTITUTE 
666 Elm Street ■ Buffalo, New York, 14263 
Department of Health ■ State of New York 
David Axelrod, M.D. 
Commissioner of Health 
Gerald P. Murphy, M.D., D.Sc. 
institute Director 
December 27, 1979 
Dr. Donald Frederickson 
Director of the National 
Institutes of Health 
Bethesda, Maryland 20205 
Dear Dr. Frederickson: 
I strongly recommend that the new proposed guidelines of November 30, 1979 
be instituted. Section I I 1-0 (p. 69218) is particularly rational. A multitude 
of real environmental problems confront us today. I believe it is irresponsible to 
waste time and energy regulating non-existent hazards. 
Recombinant DNA research has already demonstrated its worth as a tool 
in basic research and as a technique by which many of our medical and energy 
problems can be solved. This revision removes some of the impediments that 
hamper this work, and it is clearly a positive step in the direction of common 
sense in the federal guidelines. 
S i nee re 1 v . 
Dr. Kenneth W. Gross 
Cancer Research Scientist 
Department of Molecular Biology 
cb/KWG 
[ 609 ] 
