Listing of Follow-iip Clinical Studies 
LAB TESTS 
TEST pretransplant frequency autopsy 
GENE TESTS 
ADA level: 
whole blood 
yes 
monthly 
yes 
white blood cells 
yes 
bimonthly 
yes 
B and T cell lines will 
be tested for 
ADA activity when 
cells available 
dATP assay: 
white blood cells 
yes 
monthly 
yes 
urine 
NUCLEIC ACID TESTS 
RNA assays: 
white blood cells 
yes 
monthly 
yes 
in situ hybridization 
yes 
monthly 
yes 
northern 
DNA assays: 
white blood cells 
yes 
every 3 months 
yes 
per 
yes 
weekly x 4 
then monthly 
yes 
Southern 
yes 
if per positive 
yes 
B and T cell lines will 
also be tested for RNA and DNA 
when available 
G418 RESISTANCE 
Cfu-C, B cells and T 
cells will be 
tested when they 
become available 
HLA TYPING 
T CELL TESTS 
Monoclonal 
antibody markers: 
T3 , T4 , T6, T8 , Til 
yes 
yearly 
Leu 11, Dr, helper, 
suppressor, TAC 
yes 
weekly x 4 
then monthly 
yes 
Mitogens: 
PHA, CONA, PWM 
yes 
bimonthly 
yes 
Antigen proliferation: 
Candida, tetanus, sk-sd 
diphtheria, mumps 
, yes 
every 4 months 
yes 
MLR, CML 
yes 
bimonthly 
yes 
altered self vs. qp70 
yes 
every 4 months 
yes 
[212] Recombinant DNA Research, Volume 12 
