/Iri ytmrulmmt umj hi/urwmm .J (iktkm (*rmr\. 
Ci. Slanulm aiumptnalox and A W Nienhuix. 
F.dx iIjxx. Nr» Yuri. iwh. r*f *13-1*4. M 
Hu/F.li. H I) Slang. k F. Mercnla. M J. 
One. .lnMuiH ( rll (irmrl 1. ** limit. 
10. W F AaJctm«. I.. kill**N. I.. S a nd er *- Haigh. 
P J. Krclnhner. F. Ci DijuiituLik. Pr.m 
Xatl. At uJ Ni i ISA 77. <W# ( imOt. M R 
Cofwcchi. ( HI 22. 4Ni I min. A (irucxxman. M. 
(irjCN^nun. W (’ Topp. VI lltM^lun. J Vtr.J. 
32. mv « IVTVI. W F \ndcrx.* and E. Ci. 
I)ucunuki». Si i Aim 245 . HO* iJuls !W||. ( 
W la*. V.d (HI M—i 3. 1*03 limit 
31. E. Neumann. VI Vhoder Kidder. Y Wang. P. 
H HoTschneider. t.VHO J I. JUI lim2l. H 
Mcr. L Weir. I* l.cder. Pr.m Xatl AtuJ 
Si i I S. A . in press 
32 E Ci (\,Kumaki>x. |.. KJIik. L. I ce. W F 
Mm£v tfiffn 131. 73 « mi t 
33 J Vfc Ciordon and F H Ruddle. S. ir% r 214. 
1 2 44 limit; E F. Warner. T A. Sic«ari. H 
Mini/, Pr.m Mail A.mJ St i U S A 71. Mil#* 
limit. T. E. Warner r# al.. ihtJ . p 4374. F 
C\»>lanum and E IaS. Xulmrr 2*4. 
*2 iimh. R l. Hnnxier rt al.. C rll 27 223 
limit. R. D Palmiier rt al .. X miner (l,**J.i*ti 
300 Ml i im2». Ci S Vic knight . R F. Ham- 
mer E. A kuen/cl. R l. Bnnxier. ( rll 34. '35 
« IW«t: R IV Pahnrter. Ci NtusiedE R F.. 
Gclirvjx. R F. Hammer R I. Bnnxier. .\« trm r 
122 . i tm'l. 
. 14 . J. W. Gordim. Ci A Sijnpn. I) J HVokin. J 
A KarN.xa I M Ruddle. I>M. Sail A. aJ 
St i V Sa4 77. 71*1 HVMli 
35 R L Hnnxier. k A Riuhw. R E Hammer. R 
L. O’Brwn. H Arp. L Slurb. Xulmrr il^mJimt 
X* 112 limit 
14. T. E. Wagner. perx«M\al *«>mmunt«.aiHtn 
37 E l-ac>. S Rirferix. E P F.sunx. M D Bur- 
lenxha* . F D G^Unlrm. (Vtf .U. I4l|im.l|. 
U F. F Wagner. I., CoxamiNax. T A Sic* an. 
B Mini/. *A«J 35. M7nmi»R I) Palmer. T 
M Wilkie. H Y Chen.* I. Hnnxier. dW 3*. 
!•#»*# ll'MUi. F H Ruddle. fVTx* MVal x<«UMMMi> 
land 
N This ix true fnr rev csxixc genetic diseases Ikon- 
mani Jixcaxex Mill prnhaNv n*M N: treated h\ 
gene iherap> in the near future Nrxauxe ihe 
defies Use gene appears l«* make a damaging 
pnsJuct ll ix n*W n»m puxxihle l«* engineer l be 
xh»ii-o(f of an end*»gcn««tx gene, nor in replace a 
gene All ihai appears UkeH m the lore>ceaNe 
future rx i«» k able In add a n«*rmal gene 1«» a cell. 
n*M to repair nr replace a delcctnc gene altcads 
present . 
40 Ci. SmiIi R Hammer. R \LiDonaU. R Hnn- 
xier. ( rll. in press. 
41 R k Humphncx rl al.. m preparation. 
42 R I) Palmalct. H Y Own R I Hnnxier .CHI 
21. 701 i im2» 
43. R C W .Uix rt al . J Mm* ( krm 151 7X42 
limn 
44 R C W,ll,x. A H kaufmon. J. E Secgmdlcr. 
.W . p 4I<7 
45. G khour> and P Gnixx. ( rll .33. 313 limit. P 
Gross. n\A 3. I i im4i. 
44 |.. A Lai nunx Ci. k hours . C G«*rman. B 
HoMard. P Cirusx. prim Mull. AtuJ. Sti. 
( S A 7* M<liim2>.J de VdhcfV. I. CMx*m. 
C*. Tvndall. W Sduffner. Xmlm A«J» Kr\ 
It 7m< 1 1 m2 1 P F.. Berg n ml.. U.W (rid 
H *. W 3. 124#. nrn'i. 
47. P E Berg JL Popme. W F Andcrx*m. \I.J 
(rll H-J 4. I iim4i. 
4* s. I) (iillwx S I.. Mnmx.«. V T (R. S. 
Tnncgama. ( fH XV 7|7 limit. J Hanem. I.. 
(Ns«mi. W SehaiTncr. iAm/ . p "*21. C (>ieei» and 
D Haiiim*«rc. /A#d p 741 L Sinrt* R I. 
CVBnen. M IV MvVIullen. k A U41oh»m. R 
L Bnnxier. X aiarr •l..mul»mn 3l§. 2.1* i Im4i. F 
k Fujimura. P l. Demmper T Fnednvann. E 
l.innes. ( HI 23 «n iIWIi: M kaimka M 
Vaxxcur N Mnnircau. M Yams. D lilangs. 
XmimerthaUimi 2m. 7>0 iim| |. M D Walker. 
T F'dlund. A M Boulei W J Rutter. 
VW '57 limit. I S Y Own. J Mcl-.ughJm. 
D w (ndde. iAW MU. 27#» I Im4t. M J C hen 
and A W Nienhuix. J H..J (krm 254. m*n 
limit. P Mellnn. V Parker. Y (ilu/man. T. 
Mamalix CHI 27. 2”N I imi t. R k HumpAnex. 
F l.es. P. Turner. A. I). Mnulinn. A. W 
Nwnhuix. ,htJ .Rl. 171 Hm2» 
4S M Peruehn. li Hanahan. VI. Wigler. CHI 22. 
KN timoi I) M Rohttis. S Ripley. A S. 
Hcndcrxnn. R A\cl. XV 2N limit; P. J 
kretseR m c r . A. H Bn* man. VI M Huherman. 
I. Sanderx- Haigh. |.. killnx. W F Anderx*»n. 
Xmilrm At mis Krx 1. MW limit 
Ni R I. Hnftsicr. H Y Own. R Wane*. A. 
Sanhv . R I) I'almilcr. Xulmrr lljamJ.au 2H. 'V 
Hm2i. K I Mavn. R Warren. R 1) Palmiier. 
CHI 21 m tim2> 
51 k l hada rl ml . in prcpuralH*n 
52. M V Chan. P Mclkm. P ( Hamas. T Mama 
Its R Asd. C HI 32. 4*1 limit. 
53 S Wnghi. I. deBncr. F G (ir»*x\cld. R. A. 
Fla* ell. V ulmrr ll..mj*ati .US. 333 limit. 
VI A 1) Miller F S. <>ng. M G. R.*senfckl. I 
M Vemu. R. M Esanx. 5 m amt r 225. Wl 
limit 
5'. k Shinminhno and H M Tcmm. Xulmrr lljum - 
Jarntim. ><iim2i:J. StincandS. H Hughes. 
J %itJ Appl (amrl I.Vl7||m2l 
V* M A Martin. T Brsan. S. Raxheed. A. S. 
khan. Pr.rn Mail AtuJ Sr*. U.S.A 7*. 4*V2 
iimn T | H« *nncr. C O'C'nmcl. M Cohen. 
Jmj 71. 4 Tin iim2i 
57 VI Vlamn. perx^wsal xianmuntcalMMi 
Vi FrJ K. *im 4f iSn Rll. 17X4#* i25 Apnl IWUi. 
^ Rcp*Mi ul ihe RAC’ Wiving C innap «mi S««eial 
and l.lhKai Issues diseuxxcd al RAC meeting »MI 
h Fcbnun im4 
#0 H I Miller (imr 27. I iim4i lediinnall. 
M F Ynung. fwrx*MSal ci*mmunKalmn. 
42 The ereaitnn nC a Prex»deni x CiMnmixxmn no 
Human ApplwaiMMix of Cictwlie F.ngmcenng is 
tow pan iJ Nil H R 1150 
43 J Jcnxen pcrx*Mioi cnmmunK at mui. 
M TNx fovxiittm is. in fact, cnnxjxicni *iih Ihe 
ctiximg regulaiM*o *hwh slates: “The IRB 
xNmld ro*l cnnxadcr fi*xxiNe long-range effect x 
tJ apptsing Um ledge gained in the rexearch 
ax an* *ng thoxc research fixkx (hal fall 
miihtn the purs w* its rcspiMixihdils ** |45 
cm 4#I i March *. im'i 4#i 1 1 Han2)|. 
Recombinant DNA Research. Volume 12 
[ 225 ] 
