19 
Dr. Ma^ls said the group had participated in two telephone conferenoe calls 
and had met on Jamary 1 , 1981 to develop language for publication in 
the Federal Register and for subsequent consideration at the April 23-24, 
1981 RAC neet ng. He presented the draft language developed at the 
January 1 , 1981 neeting (Attachment II). 
Or. Haeis said the prcposal could be broken down into three parts: (1) a 
preanble «#iich offers the logic and reasoning behind the proposal, (2) a 
section outlining procedures to determine toxicity and (3) containment 
conditions for various potencies. He noted that for the moment the 
proposal deedt only with cloning in ^ ooli K-12 host-vector systems. 
Dr. Haas suggested that the ad hoc working group might be consulted when 
prcposeds evaluating toxins are considered. 
Mr. Thornton suggested that each RAC member take the opportunity to nake 
suggestions on the draft proposal. He tharJced the ^ hoc working group 
for their efforts. Dr. Bems suggested that Dr. Gill might be invited 
as em ^ hoc consultant to the RAC meeting at which the toxin prapos^d 
will be considered. 
XVII. FimJHE MEETING I»TES 
Mr. Thornton directed the attention of the members to tab 961 which 
outlined future meeting dates of the RAC. These are April 23 and 24, 
1981, September 10 and 11, 1981, and Jeuuary 7 and 8, 1982. 
XVIII. ADJOUBWE?^ 
The meeting was adjourned at 12:15 p.m. , January 9, 1981. 
Respectively submitted. 
( 47 ] 
