Attachment III - Page 3 
The text of the proposal as approved by the subcomnittee, with a cortparison 
to current (July 1, 1981) guidelines is attached. In £K3dition, an examin- 
ation of the state of our )ov3wledge about recombinant ENA risks, to be 
used as a rationale for change, is attached. 
We suggest the following procedures; 1) RAC consider and modify if necessary, 
the working group's proposed, and the supporting rationale staterent, 2) 
The modified proposed, and rationale be published in the Federal Register 
and elsewhere, if eppropriate, for public oo r me nt, 3) All comments be 
considered by the working group and recommendations for chemge, based on 
the oorranents, be made. The final version should once again be published 
in the Federal Register . 4) RAC take final action on the proposal. This 
might occur at the January 1982 RAC meeting, or possibly at the following 
meeting, if more time for conment is considered necessary. 
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