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Federal Register / Vol. 46. No. 233 / Friday, December 4. 1961 / Notices 
Vl-F-6-b. A request for 
presubmisaion re^ew should be 
submitted to OROA. along with the 
records involved. These records must be 
clearly marked as being the property of 
the institution, on loan to NIH solely for 
the purpose of making a determination 
under the Freedom of Information Act 
ORDA will then seek a determination 
from the HEW Freedom of Information 
Officer, the responsible official under 
HEW regulations (45 CFR Part 5], as to 
whether the records Involved (or some 
portion) are or are not available to 
members of the public under the 
Freedom of Information Act Pending 
such a determination, the records will 
be kept separate from ORDA flies, will 
be considered records of the institution 
and not ORDA. and will not be received 
as part of ORDA files. No copies will be 
made of the records. 
V1-F-5-C. ORDA will Inform the 
Institution of the HEW Freedom of 
Information Officer's determination and 
follow the institution's instructions as to 
where some or all of the records 
involved are to be returned to the 
Institution or to become a part of ORDA 
files. If the Institution Instructs ORDA to 
return the records, no copies or 
summaries of the records will be made 
or retained by HEW, NIH or ORDA. 
Vl-F-6-d. The HEW Freedom of 
Information Officer's determination will 
represent the offidal's judgment as of 
the time of the determination, as to 
whether the records involved (or some 
portion) would be exempt from 
disclosure under the Freedom of 
Information Act if at the time of the 
determination the records were in 
ORDA files and a request were received 
from them under the Act 
Appendix A of Annex E. — Exemptloos 
Un^r I-E-4 
Section I-E-4 states that exempt from 
these Guidelines are ‘'certain specified 
recombinant DNA molecules that 
consist entirely of DNA segments from 
different species that exchange DNA by 
known physiological processes, though 
one or more of the segments may be a 
synthetic equivalent A list of such 
exchangers will be prepared and 
periodically revised by the Director, 
NIH. with advice of the Recombinant 
DNA Advisory Committee, after 
appropriate notice and opportunity for 
public comment (see Section IV-E^l-b- 
(1)-(d).) Certain classes are exempt as of 
publication of these Revised Guidelines. 
The list is in Appendix A.” 
Under exemption I-E-4 of these 
revised Guidelines are recombinant 
DNA molecules that are (1) composed 
entirely of DNA segments from one or 
more of the organisms within a sublist 
and (2) to be propagated in any of the 
organisms within a sublist. 
(Classification of Bergey'$ Manual of 
Detenninativa Bacteriology, eighth 
edition. R.E. Buchanan and N.B. 
Gibbons, editors. Williams and Wilkins 
Company: Baltimore. 1974.) 
Subliat A 
1. Genus EtcharichJc 
1 Genus Shigal/a 
3. Genus Salmonella (Including Arizona] 
4. Genus Enterobocter 
3. Genus Citmbacter (including Levinaa) 
a Genus Klebeiella 
7. Genus Erwinia 
a Pteudomonoz oeruginoea, Pteudomonaz 
puUda and zeudomonaz Puormcenz 
0. Serratia marceecenz 
Subhzt B 
1. Bacilluz zubliliz 
2. Bacilluz Uchenifomiz 
a Bacilluz pumiluz 
a Bacilluz globigli 
a Bacilluz niger 
a Bacilluz nalo 
7. Bacilluz amyloliquefocienz 
0 Bacilluz alemmue 
Sublizt C 
1. Streptomycez aureofocienz 
2. Slreptomycez rimozuz 
a Streptomycee coelicolor 
Sublizt D 
1. Streptomycez grizeuz 
a Streptomycee cyaneuz 
3. Streptomycee venezueloe 
Sublizt E 
One way transfer at Streptococcuz mutanz 
at Streptococcuz loctiz DNA into 
Streptococcuz zanguiz. 
Sublizt P 
1. Streptococcuz zanguiz 
a Streptococcuz pneumoniae 
3. Streptococcuz foecoliz 
4. Strept o coccuz pyogenee 
Appendix B of Annex E. — Clasaiflcatioa 
of Microorganisms on the Basis of 
Haxard 
I. Clazzificatlon of Etiologic Agents on 
the Basis of Hazard (1) 
A dess 1 Agents 
All bacterial, parasitic fungal, viral, 
rickattslal. and chlamydial agents not 
Included In higher classes. 
B. Oess 2 Agents 
7. Bacterial Agents 
Actinobocilluz — ell species except A. mallei, 
which Is In Gass 3 
Arizona hinzhawii — all serotypes 
Bacilluz anthraciz 
Bordetella — all specie* 
Bonelia recurrenliz. B. vincenti 
Clostridium botulinum. Cl. chauvoel. Cl. 
hoemolytlcum. Cl. hiztolytlcum. Cl. novyi. 
Cl. zepticum. Cl. tetani 
Corynebocterium diptherim, C equi, C. 
haemolyticum, C pzeudotuberculoetz, C 
pyogenes, C renale 
Diplococcuz (Streptococcuz) pneumoniae 
E^ipelothrix inzidioea 
Escherichia co//— all enleropathogenic 
serotypes 
Haemophilus ducreyi H. inPuenzae 
Herellae vaginicola 
Klebsiella — ell species and all serotypes 
Leptospira Interrogans— m\\ serotypes 
Ltsterro— all species 
Mima polymorpha 
Moraxello—eW species 
Mycobacteria — all species except those 
listed In Gass 3 
Mycoplasma — all species except 
Mycoplasma mycoidee and Mycoplasma 
agalocUoe. which are in Gass 8 
Neisseria gonorrhoeae, N. meningitidis 
Pozteurello — oil spedos except those listed in 
Gass 3 
Salmonella— eti species and all serotypes 
Shigella — all specias and all serotypes 
Sphaerophoruz necrophoruz 
Staphylococcus aureus 
Streptobocilluz moniliformis 
Streptococcuz pyogenes 
Treponema caroteum, T, pallidum, and T, 
pertenue 
Vibrio fetus. V. comma, including biolype B1 
Tor. and V. parahemolyticus 
a Fungal Agents 
* ‘Actlnomycetez (Including Nocardia spedes 
and AcUnomycee species and Arochnia 
propionica) 
Bioztomycez dermatitldiz 
Cryptococcuz neoformanz 
Paracoccidioides brazUieniz 
X Parasitic Agents 
Endomoeba histolytica 
Leizhmania zp. 
Noegieria gruberi 
Toxoplasma gondii 
Toxocara caniz 
Trichinelh spiralis 
Trypanosoma cruzl 
4. Viral Rickettsial, and Chlamydial Agents 
Adenov/ruses— human— all types 
Cache Valley virus 
Coxzackie A and B viruses 
Cytomegalo viruses 
Echoviruzez — all types. 
Encephalomyocarditiz virus (EMC) 
Flanders virus 
Hart Park virus 
Hepotitiz-azzociated antigen material 
Herpes viruses— except Herpesvirus zimiae 
(Monkey B virus) which Is in Gass 4 
Coroma viruses 
Influenza viruses — all types except A/PR8/ 
34. which is in Class 1 
Langat virus 
Lymphogranuloma venereum agent 
.Measles virus 
Mumps virus 
( 309 ) 
