2 
2. Section III of the Gbidelines would be reorganized and simplified. 
All experijiients would fall into one of four classes. E^ysical contain- 
ment requireraents for some classes of experiments would be lowered. 
3. Three of five current prohibitions (I-D-2, I-D-4, amd I-D-5 in the 
c ur rent Guidelines) %ouId be listed in a new section that would con- 
tinue to require RAC review and NIH approval before initiation. 
&q3eriments currently falling inder pr^ibition I-D-1 eind I-D-6 could 
prcxeed alter IBC ^ppro^al. 
Copies of the above mentioned Ptederal Register notices as well as a sunmary 
ooiparing the cu rr ent Guidelines with the two proposals are enclosed. Comments on 
these proposals should be directed to the attention of the Director, Office of 
ReocaPinant OKA Activities, National Institutes of Health, Building 31, Room 4A52, 
Bethesda, Maryland 20205, U.S.A. 
These proposals and ooBinents on them will be considered by the RAC at its next 
meeting on February 8-9, 1982. 
( 321 ) 
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